Benzo effectiveness reduced because of other meds or crappy quality?

[nwiron]

I've noticed the strength/effectiveness of the benzos I've taken recently are greatly diminished from what I am used to.

I wanted to get some opinions from others that may have the same experience and see if it's just crappy quality or something else.

My Dr. has me on good ol' phentermine to lose weight.  Another former member made a post that, in their opinion, these two things kind of work synergistically (is that a word?...anyways, with synergy).  They said the feeling of the benzo was slightly dumbed down, but still effective.  Their meds were more along the ADHD kind, not the weight loss kind but they're all still part of the same family right?

Well, I am also on the noopept.  I couldn't find anything concrete, using google, on whether that would have any kind of reaction with the benzos. 

So, I am wondering if anyone out there has any similar experience?   Otherwise, it's just a crappy brand/batch of benzos.

And just so you know, I've tried skipping the diet pill and the noopept but doing the benzo and still get the same result...basically nothing.


Anyone's expertise is greatly appreciated!

You should talk to your doctor.

Phentermine is an upper and is going to reduce how well benzos work. This is a speedball of sorts. Adding the noopept is only going to cause more altered effects.

I take modafininl for shift work disorder before work, and a heavy dose on benzos after to sleep and I have noticed the benzos don't work as well anymore.

One thing I gotta say is, tolerance to benzos sneaks up on you. one day 10mg of diazepam will knock you on your ass then a week later 2 or 3 barley relaxes you. 

You should talk to your doctor about the combination of the three, you may be fine and just need to adjust your benzo dose.

What dose/benzo are you using? how long? has it escalated in the last month or week?

Yes, the Dr. originally had me on modafinil because of shift work.  Then said if I wanted to lose weight I couldn't have both, which made total sense.  I can only imagine what taking both would do...

I just recently got the benzos and was wondering if maybe they were a crappy quality/batch.  I skip the phentermine 2 days a week.  It's my understanding the active time for the phentermine is about 13 hours give or take.

So, this experience was taking the benzo(s) on days (actually evenings) that I skipped the phentermine and the so it had been well over 24 hours since I had taken them.  

Previously, way before all this, I was taking 1mg clonapin up to 3 times per day as needed.  So, being that I hadn't taken any benzos in a few years I thought for sure I would be feeling pretty damn good with a 2mg tablet.  It did a little bit of something, but not nearly like it used to.  And back then, that was at 1mg.

So, next time around, I tried a 2mg xanax bar.  It did LESS than the 2mg clonapin!  This shouldn't be possible right?!  That's where I started to think maybe the brand/quality/batch was crap.

This is just within this last 4 weeks as far as how long.  I don't take any benzos on the days I do the phentermine, the weird thing is, I don't get anxiety on the days I'm taking it.

I know I don't have a tolerance of the benzos built up because I'm not taking them daily.  So either the noopept has a side effect of blocking effects of benzos and I'm the first guinea pig to discover it, the phentermine is so built up in my system taking 2 days off isn't enough, or it was just a crappy batch of benzos.

I used to call clonapin my "g" pills because when I took them all the anxiety and stress just melted away and I felt mellow, laid back, and like a million dollar g-pimp.  Is it too much to expect a similar feeling now?

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But what bezos are you taking it ? and also, did you changed the brand ?
And anxiety is a common side effect of phentermine.

xanax and clonapin

Yes, anxiety is a common side effect.  Luckily, for whatever reason, I do not get anxiety on the days I am taking the phentermine.

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The K 125's are a short acting Phent. the Inamine you find is long acting (the 15's and the 30's)

Also keep in mind most of the K125 footballs that come from that I country are not real, or at least are a formulated pill from one of the labs, not that there aren't some good labs there.
Sun Pharm is usually very good, but if you check deep enough, you can special order just about any med you want them to make...Its hard to make so you will not see much on most sites. Often its just ephedra with some really cool blue dots thrown in.
The true K 125's are hard, and do not powder.  just a fyi........So I would recommend that one stay with one of the SY guys for that. We have a couple of SYs that are very good.

The Inamine is legit from the couple of vendors here. Always go for the 30's and they are supposed to be bid.

Phent isn't an amphetamine, It metabolizes into an amphetamine. Therefore it is classified by most as such.
It does not have the initial "punch"  Vs Adderall a true amphetamine with dex that goes right to the spot .

All that considered, does it decrease the effect of the benzos... the answer is yes. If you are talking about short term use of benzos.
If your a long time user of benzos, and take phent.. then its probably tolerance.
You will find it best to switch between benzo types... ativan, valium, klonipin, bromazepan ect....
You will need to take a benzo holiday at times...

Phentermine response is best slowed with Benadryl. 50 mg po. x1.
Careful though, if you stop phent too fast, your going to sleep for days.
Be sure to take the B12 Vitamin.. buy only the Methylcobalamin type of b12 as the Cyanocobalamin is actually bad for the body, Chromium and plenty of water with phent

Dont forget as well, Benzos are a really hard drug to withdrawal from, even life threatening. 10 to 14 days after you stop benzos, you are at the greatest threat for prolonged seizures, and death. Most doctors just don't remember this, and think a 3 day detox from benzo is ok... idiots..
Stopping benzos all together and starting phent, is going to speed up your metabolism, so your benzo w/d days are going to be sooner.
I think you might find a very good expert on here on how to taper well.... Just ask and I am sure you will get a response.
Hope some of this helps.. its just what I saw on tv once

..

VERY good info to have, thank you!  The phentermine is legit script 37.5's.  I thought changing benzos would fix the issue too.  No luck yet.  What's the B12 and Chromium do?  Or you mean take that once it's time to come off the Phent?

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Phentermine is a stimulant and boosts dopamine, and benzodiazepines work by inhibiting Gaba receptors. They are working in opposition of each other and thus making them both probably less effective.

Do you know how long the phentermine stays active in the system that it would act in opposition of the benzos?  I skip 2 days a week on the phentermine and on the days I'm not taking is when I tried the benzos.  Also, do you happen to have any info about the noopept and what effect it could have on the benzos?

what brand of benzo....your xanax and kpin?

[Goyakla1]

I agree.. Perth.is an upper cfr. Benzos... So the advise to shift to different Benzos is really good.. And if u Can take a break.. Just a Day or 2..ur tolerance Will be lower. But isnt there another drug u could use indstead of Phentemine..just a ?..

[classemlaff]

The phent is the only thing that has really worked that I've tried. And it's worked very well. After this month I'm getting moved to another long term med called contrave. I like the phent because I have to consciously make myself eat. Whereas before I turned to food whether it was stress, boredom, happy, sad, etc... and didn't even realize it. The phent switches off my hunger button and when I first started taking it the ridiculous energy buzz was an added bonus.

[Goyakla1]

If u Got anxeity problems i would try to talk to the doc about Mitrazpin.. It has worked for me..and taken before bedtime with a normal sleeping pill it Will normaly get me 7 h.of good sleep.

[classemlaff]

I'm just going to stick to what I have for now. Knowing that in less than a month I will be on something new, then you are right in that the other med may help with weight loss and anxiety. Won't know until I switch. I will have to ask the dr. how to switch because surely you don't just quit taking the phent and switch right over to something new. Maybe there is a week where I don't take anything? Someone mentioned when you stop taking phent you will be super tired for days. I just hope skipping 2 days per week is helping with that part. I do feel more tired on the days I don't take it, but nothing terrible (like after I took that damn hydroxizine hcl).

[Goyakla1]

@james.. I get 45 mg at Night.. And have taken Them since 2006. It takes time before they kick in.. But i do get a good sleep at Night. No groggy Feeling the next Morning. But all ppl are different. But if i want a nap in the weekend i talk a half and 5 mg of vals and sleep for 4 hours. Hope the answer helped u. If NOT ask again.

[classemlaff]

Hey all, was gone for a while just wanted to give a quick update. I have been off the phen for about a month now, it helped me lose nearly 60 lbs in about 3.5 months, YAY!

The Dr. prescribed me Contrave, but I never got it. It seemed stupid to pay $45 for a month's worth of a small dose of antidepressant and something that negates the effects of alcohol and benzos. So, I'm on my own. Doing good so far but damn I do miss that phen feeling!

Anyways, I can def say with 100% guarantee it was the phen making the benzos not work very well. I took 2mg of xanax the other day for the 4th of July festivities and it knocked me on my ass! Like an idiot I had a couple beers, which I haven't drank in about 2 months, and yeah they weren't doing anything for the anxiety/panic/hyperventilating. So I took the xanax and learned the hard way there's a REASON they say don't drink when you are on benzos.

It didn't do any of the medical stuff like kill me or depress my breathing or any of that scary stuff. I mean DON'T DO IT because of how it makes you act and then you totally forget what you did when the next day comes around. No problem though my family was sure to tell me all about it! I passed out on the couch after asking people the last time they had been happy, like REALLY happy and was asking my gf why she smelled like popcorn over and over like a broken record (she was smoking a cigarette). And to top it all off I missed the local fireworks show because I had already passed out!

So now that phen is a thing of my past 1mg of xanax works like a charm when needed.

[IceWizard]

Congrats on the 60#'s!!

That was quite an effort to do in that length of time indeed! My sister has been a pretty big girl all her life, so I know how she struggles everyday with weight... And being from the south, it's hot down there and well it doesn't help having a few extra pounds!!

So great job and keep up the great work!!

Ice

[classemlaff]

Congrats on the 60#'s!!

That was quite an effort to do in that length of time indeed! My sister has been a pretty big girl all her life, so I know how she struggles everyday with weight... And being from the south, it's hot down there and well it doesn't help having a few extra pounds!!

So great job and keep up the great work!!

Ice

Thanks Ice!

It's hard to admit when you're addicting to food.  Just saying it is laughable and sounds ridiculous, but it's true.  It's not heroin or pain pills or alcohol but in one way it's worse because you have to eat.

I had been one of those that would lose then gain it back plus more over and over again.  I never could just stick to a diet and exercise.  In high school I was 6'2" and about 185, fast forward almost 20 years later and I was 350.  I'm at about 290 now and still losing, hope I can get down to 240 or so.  What kicked me in the ass was when my Dr. said my blood A1C was 7.4!  That's diabetes folks.  Not borderline or high risk...that's "you got diabetes".  So, with their help and my determination I got my a1c down to 5.4 which is "normal".  I won't be going back this time to having to deal with the beetus that's for sure.  And any of you that have it, I'm sorry and my heart goes out to you.  I know what it's like now to feel like crap and be tired and have ZERO energy every friggin day, but not even realize it's a problem or tricking myself into thinking meh, it's not that bad.  In my situation I caught it quick enough, who knows how long it had been that high.

I don't know if it would help your sister or anyone else struggling for that matter, but I started by doing the paleo (caveman) diet.  I chose it because you can eat more than on other diets, it's just very restrictive.  You pretty much cut out everything that's not a meat, vegetable, fruit or nut.  If it's not any of those 4 things then you can't eat it.  If it is on the list you can pretty much have as much as you need.  You will lose weight quick though and if you have the discipline to stick to it whether through your own self discipline or chemical help (like phentermine) then it will keep coming off.

[synth]

SSRI antidepressants like zoloft, prozac, paxil will decrease the effects of benzodiazepines