05-09-2018, 07:41 PM
Anxietyguy, doxepin and trazodone induce sedation through different mechanisms, so it might be worth trying both. Doxepin at low doses is essentially a H1-antagonist like Benadryl. Trazodone at low doses is also a H1-antagonist but also is a 5HT2C-antagonist.
Personally, trazodone makes me feel like garbage. I threw out the box after trying it 2 or 3 times. I keep doxepin around, and if I really can't get some sleep, just 1 mg helps.
Personally, trazodone makes me feel like garbage. I threw out the box after trying it 2 or 3 times. I keep doxepin around, and if I really can't get some sleep, just 1 mg helps.