11-22-2017, 12:22 PM
(11-21-2017, 01:30 PM)blandy Wrote: I realise you're asking for other review sites but feel i need to say a little on using Tramadol for depression:-Hey Blandy,
I couldn't agree more that tram is an excellent antidepressant better than anything else i ever tried for the condition but like all meds its not with out its risks. For people who may not know Tramadol is both a fully synthetic opoid and and an SSNRI. The problem I and many people that i know have found is that tolerance raises quickly and the seizure threshold is quite low meaning that as little as 500mg can put you at risk of a seizure. Also if you are already taking an antidepressant SSRI then you are at risk of serotonin syndrome both this and seizures can result in fatality.
I'm not trying to scare anyone or teach people to suck eggs, I'm just sharing my knowledge and experience.
Feel free to PM me with any questions i would be happy to help.
I agree with everything that you said and have actually seen a lot of it in action in the practice where I used to work. Tram definitely brings it's own unique set of risk's. I used to only recommend it for refractory cases of depression and, even then, at the lowest effective dose and for fairly short courses. Hard to believe that it took until 2014 for the DEA to finally consider it a controlled substance in all 50 states. But throwing it on the schedule as a 4 surprised me, even back then. With the conventional opioid crunch now underway, Tram will soon gain even more popularity and scrutiny, and surely make it's way up to a 2. I wrote in a former post that veterinarian's are hardly scripting for them any more, and that drug was staple in their practices. What a shame. Regards, Rafter.