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Benzo's as appetite stimulant's
#21
(12-01-2017, 11:50 AM)OldBoy Wrote:
(12-01-2017, 02:26 AM)Rafterman Wrote:
(11-30-2017, 11:13 PM)OldBoy Wrote: I've often wondered why I seem to have a much more normal appetite when being treated with benz@s...I'm the sort who skips breakfast in favor of an extra twenty minutes sleep, forgets to eat lunch because there is always something more important to do / worry about than fixing a sandwich, and now that I live alone, for the most part have soup, a canned vegetable, and perhaps a sandwich for dinner.

That's when I'm untreated, or miss a dose of medication.  When I'm being actively treated with a benz@ anti-anxiolytic, I eat a normal breakfast, pack a lunch to take with me, and cook something reasonably appetizing for dinner, I'll even snack on popcorn or pecans in the evenings.

I've always surmised that the calming effect of the medication makes one worry less about over-eating, or simply produces a normal appetite by virtue of relieving the stress and anxiety that cause loss of appetite, but I could be absolutely wrong on that count, I've done no research and read no studies to support my conclusion.
Hey OldBoy,
The benzo's increase appetite through a complex process that makes food and drink seem more palatable to the brain. I imagine that there is the secondary effect of reduced anxiety helping the appetite along a little further. Here's an PubMed piece that explains how they work in animals. With the science in place behind it, you would think that benzo's would be approved as an appetite stimulant, but the FDA thinks that the risk/reward ratio is upside down. How wrong they are. They do not take anorexia seriously enough. It is a killer. In any event, here is the piece.  Take care.  https://www.ncbi.nlm.nih.gov/m/pubmed/7770192/

Excellent, Rafterman.  The article's abstract neatly destroys my own theory, and the text (fortunately, I still have access to ScienceDirect via my former employer, if only for six more months) is a great read.  Berridge and Peciña demonstrate pretty conclusively that perceived palatability of food and fluids is enhanced by benz@ agonists, and that the anti-anxiolytic effect of the medications is a (remotely) possible, but only secondary, if at all extant influence on appetite.

Really appreciate the link my friend, much better reading over breakfast than the newspaper Smile

Lol, my pleasure, OB. My best to you.  RM
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#22
(11-05-2017, 08:17 AM)Rafterman Wrote: Hey all,
After 30 years of counseling emotionally-troubled client's, I have seen my share of anorexia. There are 4 or 5 conventional appetite stimulant's available by script. Most are used by patient's undergoing chemo. Not once have I seen one of our prescribing doc's write for one of those drugs. We used benzo's to break through the anorexia. When the anorexia is caused by a fear of gaining weight (anorexia nervosa), treatment with benzo's was only moderately effective. When it was treated by lack of hunger for no apparent cause (anorexia), the results were stunning. Very few cases that weren't resolved. After a couple of weeks, we could remove the med and the lust for eating continued! Of course, we live in a world of benzophobic doc's who rather prescribe harsh, potentially life-threatening medications in place of a simple benzo. My personal opinion is that benzo's are a Godsend. I can't think of a medication that I have seen help more people. Yes, there are abusers...and they harm themselves and they harm legit users), but the majority of scripts are written for the truly needy. Benzo's can save lives, just as much as an antibiotic, or a heart medication, or a blood pressure drug can. Yet so many have trouble getting access. Anorexia is only one example. It's an under-reported problem in the US. It could all but be wiped out if doc's wouldn't be so hesitant to give a patient what they need.

are you saying that in your country they use  benzos to help cure anorexia?.   In the UK we just get a nose hose.  I  had a bmi of 14. something, I was given NG tube, ensure, a dietitian ,  and had to be weighed by me GP. as soon as my bmi was 17 I was described as weight restored ( despite the fact anything under 17.5 is classified as anorexic.  When I look back there was NOTHING wrong with my body at all, in fact I was slim but toned, but when you have to weighed as part of your job, it does mess with how you look.  I was never given any appetite stimulators nor benzos.  Just stuck in room with a nose hose.
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