02-05-2019, 10:53 PM
That was really the first of the anti depressants. it was called an MAO then. My doctor sister reminded me of trauma in my life. she paid for a psych for me. i would not have to deal with the abuse when older then.
My second AD he put me on. They all suck. They make it impossible to concentrate. And I was spending 25 yrs in school to become a doctor of law. May as well make it count.
So second AD we try, and I was the first group to do so, was the MAO. And no one knew a damned thing about it but sure they did prescribe it for the rewards the drs. get.
I took it. I got bronchitis and pneumonia as per usual. And i had tickets to a big concert. Blind Date. My same pharmacist whom filled the MAO pills, never told me that I cannot take any codeine med for bronchitis. None. I can become paralyzed and that paralyzed bit may never go away. So my pharmacist filled a heavy codeine cough syrup.
Off i go and as the concert starts, I go down. Paralyzed. The cops that ran to me, had me call my Dr. sister. She checked her new PDR and saw the possible side effects of MAOs. And told me we hope the paralysis wears off. And the cop carried me and i got the front aisle.
It wore off.
I would never go near any medicine that could permanently paralyze me if i took a medicine to lessen my coughing when i have an upper respiratory.
Further, I could not think clearly on that crap.
And school was far more important. *whom knew i would develop autoimmunes that bring on changes in the brain*
Ok, i never discussed with the nutjob doctor about abuse. And he would get so angry at me cuz i figured out psych kept the clock in plant next to me. Oh he would scream. And I would say I cannot concentrate. But, for a psych, he had a really hard time concentrating so he must have thought that was normal. It was a large bldg on central park south or west, and one appt he jumped up screaming cuz he heard a tiny piano song in the far distance.
So that is the type of doctor whom prescribes that med. He also dx'd me as a catholic prude, which i doubt anyone else would have. I had some issues with men. And that i put others before me. Yeah, so?
And then i did research because i collapsed down the stairs at highschool.
Side Effects of
MAOIs
FIND A PHARMACIST WHO OFFERS GENETIC TESTING FOR MAOIS
Home>Side Effects>MAOIs
Description: MAOIs (monoamine oxidase inhibitors) are an older class of antidepressant that carry the risk of considerable side effects and drug interactions. Modern MAOIs used to treat depression (mostly atypical depression), include phenelzine, selegiline, or tranylcypromine. Selective MAOI inhibitors (selegiline, rasagiline) may be prescribed to people with Parkinson’s disease.
(Australasian Psychiatry “MAOIs – does the evidence warrant their resurrection,” Aug 2016).
Mechanism of Action
As the name implies, an MAOI blocks the action of a chemical called the “monoamine oxidase” enzyme. Inhibiting the monoamine oxidase enzyme makes several chemical levels rise. These include the common neurotransmitters (brain chemicals) dopamine, serotonin, and norepinephrine. (Journal of Clinical Psychiatry “Mechanism of action of antidepressant medications,” Apr 1990).
Serious Side Effects of MAOIs: Hypertensive Crisis and Serotonin Syndrome
People who eat substantial amounts of tyramine in conjunction with MAOIs may experience an unsafe increase in norepinephrine levels. Too much norepinephrine may lead to a state called “hypertensive crisis,” which is a dangerously high blood pressure level. Another potentially severe side effect of MAOIs is serotonin syndrome, which causes elevated blood pressure, agitation, tremor, sweating, and other symptoms. In severe cases, serotonin syndrome may lead to seizures, muscle destruction, coma and death. (CNS Drugs “Current place of monoamine oxidase inhibitors in the treatment of depression,” Oct 2013).
Common Side Effects of MAOIs
Nausea occurs in more than 10% of people who take an MAOI, according to Journal of Clinical Psychiatry “Mechanism of action of antidepressant medications” (Apr 1990).
Other relatively common side MAOI effects, according to CNS Drugs “Current place of monoamine oxidase inhibitors in the treatment of depression” (Oct 2013) include:
Headaches
Sleeplessness
Dizziness
Dry mouth
Drowsiness
Low blood pressure
Abdominal pain
Urinary problems
Understand Your Risks with the Rxight® Genetic Test
The Rxight® pharmacogenetic testing program is designed to provide patients who are considering an MAOI or who are currently on an MAOI with a profile of their own gene variants and the corresponding chemicals in the liver responsible for breaking down and processing MAOIs. Additionally, an entire suite of over 200 prescription and over-the-counter medications across 50 clinically relevant drug classes are analyzed based on a simple DNA cheek swab.
How Does Pharmacogenetic Testing Work?
PGx testing with Rxight® specifically tells you if your genetic makeup makes the activity of these enzymes higher or lower than normal, thus making some medications ineffective or, worse, potentially dangerous or fatal. This could have important ramifications for side effects and drug effectiveness, and guide your prescriber in finding the safest dose or if necessary an alternative medication.
(Read more about psychiatric medication side effects and genetic testing for antidepressant response.)
a
Contributors to this Article:
Michael Sapko, MD, PhD; Deborah Kallick, PhD, Medicinal Chemistry
Read more about Rxight® Genetic Testing For Depression Medication
My second AD he put me on. They all suck. They make it impossible to concentrate. And I was spending 25 yrs in school to become a doctor of law. May as well make it count.
So second AD we try, and I was the first group to do so, was the MAO. And no one knew a damned thing about it but sure they did prescribe it for the rewards the drs. get.
I took it. I got bronchitis and pneumonia as per usual. And i had tickets to a big concert. Blind Date. My same pharmacist whom filled the MAO pills, never told me that I cannot take any codeine med for bronchitis. None. I can become paralyzed and that paralyzed bit may never go away. So my pharmacist filled a heavy codeine cough syrup.
Off i go and as the concert starts, I go down. Paralyzed. The cops that ran to me, had me call my Dr. sister. She checked her new PDR and saw the possible side effects of MAOs. And told me we hope the paralysis wears off. And the cop carried me and i got the front aisle.
It wore off.
I would never go near any medicine that could permanently paralyze me if i took a medicine to lessen my coughing when i have an upper respiratory.
Further, I could not think clearly on that crap.
And school was far more important. *whom knew i would develop autoimmunes that bring on changes in the brain*
Ok, i never discussed with the nutjob doctor about abuse. And he would get so angry at me cuz i figured out psych kept the clock in plant next to me. Oh he would scream. And I would say I cannot concentrate. But, for a psych, he had a really hard time concentrating so he must have thought that was normal. It was a large bldg on central park south or west, and one appt he jumped up screaming cuz he heard a tiny piano song in the far distance.
So that is the type of doctor whom prescribes that med. He also dx'd me as a catholic prude, which i doubt anyone else would have. I had some issues with men. And that i put others before me. Yeah, so?
And then i did research because i collapsed down the stairs at highschool.
Side Effects of
MAOIs
FIND A PHARMACIST WHO OFFERS GENETIC TESTING FOR MAOIS
Home>Side Effects>MAOIs
Description: MAOIs (monoamine oxidase inhibitors) are an older class of antidepressant that carry the risk of considerable side effects and drug interactions. Modern MAOIs used to treat depression (mostly atypical depression), include phenelzine, selegiline, or tranylcypromine. Selective MAOI inhibitors (selegiline, rasagiline) may be prescribed to people with Parkinson’s disease.
(Australasian Psychiatry “MAOIs – does the evidence warrant their resurrection,” Aug 2016).
Mechanism of Action
As the name implies, an MAOI blocks the action of a chemical called the “monoamine oxidase” enzyme. Inhibiting the monoamine oxidase enzyme makes several chemical levels rise. These include the common neurotransmitters (brain chemicals) dopamine, serotonin, and norepinephrine. (Journal of Clinical Psychiatry “Mechanism of action of antidepressant medications,” Apr 1990).
Serious Side Effects of MAOIs: Hypertensive Crisis and Serotonin Syndrome
People who eat substantial amounts of tyramine in conjunction with MAOIs may experience an unsafe increase in norepinephrine levels. Too much norepinephrine may lead to a state called “hypertensive crisis,” which is a dangerously high blood pressure level. Another potentially severe side effect of MAOIs is serotonin syndrome, which causes elevated blood pressure, agitation, tremor, sweating, and other symptoms. In severe cases, serotonin syndrome may lead to seizures, muscle destruction, coma and death. (CNS Drugs “Current place of monoamine oxidase inhibitors in the treatment of depression,” Oct 2013).
Common Side Effects of MAOIs
Nausea occurs in more than 10% of people who take an MAOI, according to Journal of Clinical Psychiatry “Mechanism of action of antidepressant medications” (Apr 1990).
Other relatively common side MAOI effects, according to CNS Drugs “Current place of monoamine oxidase inhibitors in the treatment of depression” (Oct 2013) include:
Headaches
Sleeplessness
Dizziness
Dry mouth
Drowsiness
Low blood pressure
Abdominal pain
Urinary problems
Understand Your Risks with the Rxight® Genetic Test
The Rxight® pharmacogenetic testing program is designed to provide patients who are considering an MAOI or who are currently on an MAOI with a profile of their own gene variants and the corresponding chemicals in the liver responsible for breaking down and processing MAOIs. Additionally, an entire suite of over 200 prescription and over-the-counter medications across 50 clinically relevant drug classes are analyzed based on a simple DNA cheek swab.
How Does Pharmacogenetic Testing Work?
PGx testing with Rxight® specifically tells you if your genetic makeup makes the activity of these enzymes higher or lower than normal, thus making some medications ineffective or, worse, potentially dangerous or fatal. This could have important ramifications for side effects and drug effectiveness, and guide your prescriber in finding the safest dose or if necessary an alternative medication.
(Read more about psychiatric medication side effects and genetic testing for antidepressant response.)
a
Contributors to this Article:
Michael Sapko, MD, PhD; Deborah Kallick, PhD, Medicinal Chemistry
Read more about Rxight® Genetic Testing For Depression Medication
It is Well with My Soul