Increasing bioavailability of benzo's

[Rafterman]

Reporting back on trial #1.  SL @lpr@x 1mg
No-where near as nasty as I had imagined. Which could be due to (a) I was catastrophising how bitter it would be, or (b) Alpr@x doesn't actually contain much bitter-alp to begin with.   I'd tend to go with (a) as I've been happy with this brand over time.

To the test: I thought I felt something at 6 mins, then decided not; then again at about 20mins, and then decided not.
But at 45mins I definitely felt a rush of relaxation.
So I'm left wondering if I didn't crush down fine enough for SL - but that the vastly increased surface area of the powder hitting my stomach allowed for much faster absorption compared to the usual tablet. To this end tomorrow I will try for better SL by letting a tab dissolve very slowly under my tongue and aiming to swill not swallow.
It's also likely that my expectations are set far too high for a measly1mg dose.
I wont take more than 1mg during the working week - but am prepared to go higher on a Friday night or Saturday....
Enthusiasm for the cause is one thing, but there's part of me that knows that applying pressure - or trying to race - towards relaxation is invariably counterproductive.

I did some reading today. A 2013 paper titled 'Benzodiazepine Pharmacology and Central Nervous System–Mediated Effects' specifically mentions Loraz is well absorbed after SL, reaching peak levels in 60 minutes. Would be easy to visit any of our favored vendors to assist with product that could allow for a comparison between Lora and Alp.
Hahaha.   Like we don't have enough to do already.

RM, I am interested in your suggestions of where to go from here.
Thanks and Regards,
R

Howdy Rich,
Man, your posts are great. If I weren't sick right now, I would make a longer response to each of them. I also always crush up my meds in order to provide more surface area for absorption. I have gotten lazy over the years and now do it with my front teeth, being careful not to lose any in the natural indentations of said teeth. That is if I plan to swallow. To go SL, I crush first at a remote location, as do you. I find that many brands of ALP have a thin shell around them. I never really understood why the manufacturer would do that because it actually discourages sublingual use. Many people would just like to a pop a tab under the tongue and be done with it. You know that the manufacturers realize there is some market for forms that would lend themselves to sublingual administration  because they used to put out Ativan in a thin breathsaver-like strip. So you would think the same manufacturer would omit the thin shell in their other benzo products.

Please let us know your results from tomorrow, as you let the tab dissolve slowly sublingually. Don't be afraid to let it linger there. I think, of course, that the level of impact will vary dependent upon a few different things... size of dose, tolerance level, bioavailability of ALP in the formulation that you were using, and how empty the person is when they getting the test. You have brought out all these points already. Just curious, but you like those Alprax? I have heard varying reviews.  Cheers, RM