AstraZeneca bags another cancer drug deal, this time with Inovio

[IceWizard]

Mon Aug 10, 2015 4:24am EDT

LONDON (Reuters) -
AstraZeneca has clinched its third deal in less than a week to bolster its strategically important cancer drug pipeline by signing up rights to an experimental immune system-boosting medicine from Inovio
Pharmaceuticals.

Inovio will get $27.5 million upfront and potential future payments of up to $700 million, depending on the success of its INO-3112 immunotherapy, which targets cancers caused by human papillomavirus (HPV) types 16 and 18.

AstraZeneca said on Monday its MedImmune
biotech unit would study INO-3112 in combination with other immunotherapy drugs. INO-3112, which is in Phase I/II clinical trials for cervical and head and neck cancers, works by generating killer T-cell responses that are able to destroy HPV 16- and 18-driven tumors.
The two HPV types are responsible for more than 70 percent of cervical cancer. The deal follows other recent immuno-oncology
tie-ups by AstraZeneca with Sosei subsidiary
Heptares and Mirati.


(Reporting by Ben Hirschler; Editing by Susan
Fenton)