04-18-2021, 12:51 AM
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Team of American and Chinese Scientists Announces
Human-Monkey Hybrid Embryos Have Been Created
By Andrew Jose,
The Western Journal
Published April 16, 2021 at 10:15am
A team of U.S. and Chinese scientists have produced a series of human-monkey hybrid
embryos in a study released Thursday that is raising critical bioethical questions about
its experiments and their implications.
In the study funded by the National Natural Science Foundation of China and published
in the journal Cell, scientists took six-day-old macaque monkey embryos and injected
25 human cells into each of them.
The type of human cells used are extended pluripotent stem cells, which can help develop
both embryonic and extra-embryonic tissues, according to a Cell news release.
One day following the injections, human cells were found alive in 132 of the hybrid embryos.
Ten days later, 103 of them were still alive and growing. However, survival rates started
dropping to the point that by day 19, only three of them were alive. The embryos that did
survive, however, had a high percentage of human cells in their mix.
The researchers conducted this study as part of an effort to discover new methods of
creating organs for those in need of transplants.
“This is one of the major problems in medicine — organ transplantation,” Juan Carlos Izpisua
Belmonte, one of the study’s co-authors, told NPR. “The demand for that is much higher
than the supply.”
Despite the supposedly altruistic goal of the researchers, the study raised important
questions concerning its ethics.
“My first question is: Why?” Kirstin Matthews of Rice University’s Baker Institute told NPR.
“I think the public is going to be concerned, and I am as well, that we’re just kind of pushing
forward with science without having a proper conversation about what we should or should not do.”
The most significant concern scientists who spoke with the outlet had is somebody pushing
the study further by creating a baby out of such hybrid embryos. Some worried that the
human cells could become part of the product creature’s brain, raising new concerns on
legislating on issues surrounding the resulting being.
“Should it be regulated as human because it has a significant proportion of human cells in it?
Or should it be regulated just as an animal? Or something else?” Matthews said.
“At what point are you taking something and using it for organs when it actually is starting
to think and have logic?”
A third concern that scientists who spoke with NPR shared was the resulting animals producing
human sperm and eggs.
“Nobody really wants monkeys walking around with human eggs and human sperm inside them,”
Stanford University bioethicist Hank Greely told NPR. “Because if a monkey with human sperm
meets a monkey with human eggs, nobody wants a human embryo inside a monkey’s uterus.”
In 2015, the National Institutes of Health issued a ban on federal funding for research projects
involving injecting human cells into animal ones to create half-animal and half-human organisms,
according to the federal register.
In 2016 however, the NIH contemplated lifting the moratorium, which would permit taxpayer
dollars to be used to fund such studies.
This article appeared originally on The Western Journal.
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